Ownership Submission
FORM 3
 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
  Invus Public Equities, LP
 2. Date of Event Requiring Statement (Month/Day/Year)
05/10/2008		 3. Issuer Name and Ticker or Trading Symbol
ANTIGENICS INC /DE/ [AGEN]
(Last)
(First)
(Middle)
750 LEXINGTON AVENUE, 30TH FLOOR		 4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director __X__ 10% Owner
_____ Officer (give title below) _____ Other (specify below)
5. If Amendment, Date Original Filed(Month/Day/Year)
(Street)

NEW YORK, NY 10022		 6. Individual or Joint/Group Filing(Check Applicable Line)
___ Form filed by One Reporting Person
_X_ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4)		 2. Amount of Securities Beneficially Owned
(Instr. 4)		 3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)		 4. Nature of Indirect Beneficial Ownership
(Instr. 5)
Common Stock 3,533,333
D (2)
 

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. SEC 1473 (7-02)
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Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 4)		 2. Date Exercisable and Expiration Date
(Month/Day/Year)		 3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)		 4. Conversion or Exercise Price of Derivative Security 5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)		 6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares
Common Stock Warrants (right to buy) 07/09/2008 01/09/2018 Common Stock 3,333,333 $ 3 D (1) (2)  

Reporting Owners

Reporting Owner Name / Address Relationships
Director 10% Owner Officer Other
Invus Public Equities, LP
750 LEXINGTON AVENUE
30TH FLOOR
NEW YORK, NY 10022		     X    
Invus Public Equities Advisors, LLC
750 LEXINGTON AVENUE
30TH FLOOR
NEW YORK, NY 10022		     X    
Ulys, LLC
750 LEXINGTON AVENUE
30TH FLOOR
NEW YORK, NY 10022		     X    
DEBBANE RAYMOND
750 LEXINGTON AVENUE
30TH FLOOR
NEW YORK, NY 10022		     X    

Signatures

Invus Public Equities, L.P., By: Invus Public Equities Advisors, L.L.C., its general partner, By: /s/ Raymond Debbane 05/12/2008
**Signature of Reporting Person Date
Invus Public Equities Advisors, L.L.C., By: /s/ Raymond Debbane 05/12/2008
**Signature of Reporting Person Date
Ulys, L.L.C., By: /s/ Raymond Debbane 05/12/2008
**Signature of Reporting Person Date
/s/ Raymond Debbane 05/12/2008
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 5(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) The Reporting Person also owns warrants to purchase 3,333,333 Units, at an exercise price of $3.00 per Unit. Each Unit consists of one share of Common Stock and one warrant to purchase one share of Common Stock at an exercise price of $3.00 per share, as adjusted from time to time. The warrants described in this footnote are not currently exercisable and will not become exercisable until the occurrence of certain events with respect to the Issuer, which events are not solely within the control of the Reporting Person, are not related to the passage of time, and are not related to the market price of the Issuer's stock.
(2) This report is filed jointly by Invus Public Equities, L.P., Invus Public Equities Advisors, L.L.C., Ulys, L.L.C. and Raymond Debbane. The reported securities are owned directly by Invus Public Equities, L.P. Invus Public Equities Advisors, L.L.C. is the general partner of Invus Public Equities, L.P. Ulys, L.L.C. is the managing member of Invus Public Equities Advisors, L.L.C. Raymond Debbane is the sole member of Ulys, L.L.C. Accordingly, each of Invus Public Equities Advisors, L.L.C., Ulys, L.L.C. and Raymond Debbane may be deemed to be indirect beneficial owners of the reported securities. Each of Invus Public Equities Advisors, L.L.C., Ulys, L.L.C. and Raymond Debbane disclaims beneficial ownership of the reported securities, except to the extent of its or his pecuniary interest therein.

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