Ownership Submission
FORM 3
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number: 3235-0104
Expires: January 31, 2005
Estimated average burden hours per response... 0.5

(Print or Type Responses)
1. Name and Address of Reporting Person *
  Berkley Capital Management Ltd.
2. Date of Event Requiring Statement (Month/Day/Year)
01/29/2015
3. Issuer Name and Ticker or Trading Symbol
Mirati Therapeutics, Inc. [MRTX]
(Last)
(First)
(Middle)
C/O CAY HOUSE P.O. BOX N-7776 E.P., TAYLOR DRIVE LYFORD CAY
4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director __X__ 10% Owner
_____ Officer (give title below) _____ Other (specify below)
5. If Amendment, Date Original Filed(Month/Day/Year)
(Street)

NEW PROVIDENCE, C5 
6. Individual or Joint/Group Filing(Check Applicable Line)
___ Form filed by One Reporting Person
_X_ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4)
2. Amount of Securities Beneficially Owned
(Instr. 4)
3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)
4. Nature of Indirect Beneficial Ownership
(Instr. 5)
Common Stock 0
D (1)
 
Common Stock 1,950,732
D (2)
 
Common Stock 429,340
D (3)
 

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. SEC 1473 (7-02)
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 4)
2. Date Exercisable and Expiration Date
(Month/Day/Year)
3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)
4. Conversion or Exercise Price of Derivative Security 5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)
6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares

Reporting Owners

Reporting Owner Name / Address Relationships
Director 10% Owner Officer Other
Berkley Capital Management Ltd.
C/O CAY HOUSE P.O. BOX N-7776 E.P.
TAYLOR DRIVE LYFORD CAY
NEW PROVIDENCE, C5 
    X    
Boxer Asset Management Inc.
C/O CAY HOUSE P.O. BOX N-7776 E.P.
TAYLOR DRIVE LYFORD CAY
NEW PROVIDENCE, C5 
    X    
MVA Investors, LLC
C/O CAY HOUSE P.O. BOX N-7776 E.P.
TAYLOR DRIVE LYFORD CAY
NEW PROVIDENCE, C5 
    X    
LEWIS JOSEPH
C/O CAY HOUSE P.O. BOX N-7776 E.P.
TAYLOR DRIVE LYFORD CAY
NEW PROVIDENCE, C5 
    X    
Boxer Capital, LLC
440 STEVENS AVE, SUITE 100
SOLANA BEACH, CA 92075
    X    

Signatures

Boxer Capital, LLC, By: /s/ Aaron Davis 02/02/2015
**Signature of Reporting Person Date

Boxer Asset Management Inc., By: /s/ Jefferson Voss 02/02/2015
**Signature of Reporting Person Date

MVA Investors, LLC, By: /s/ Christopher Fuglesang 02/02/2015
**Signature of Reporting Person Date

Joseph Lewis, By: /s/ Joseph C. Lewis 02/02/2015
**Signature of Reporting Person Date

Berkley Capital Management Ltd., By: /s/ Jefferson Voss 02/02/2015
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 5(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) Berkley Capital Management Ltd. ("Berkley Capital") may be deemed to be a member of a "group" for purposes of Section 13(d) of the Securities Exchange Act of 1934, as amended, consisting of (i) Berkley Capital, (ii) Boxer Capital, LLC ("Boxer Capital"), (iii) Boxer Asset Management Inc. ("Boxer Management"), (iv) MVA Investors, LLC ("MVA Investors"), and (v) Joseph Lewis (collectively, the "Boxer Group"). Joseph Lewis is the sole indirect owner of and controls Berkley Capital.
(2) These securities are owned directly by Boxer Capital, and indirectly by Boxer Management and Joseph Lewis, by virtue of their ownership in Boxer Capital.
(3) These securities are owned directly and solely by MVA Investors, which has sole voting and dispositive power with respect to these securities. Each member of the Boxer Group other than MVA Investors disclaims beneficial ownership of these securities to the extent it or he does not have a pecuniary interest therein.

Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, See Instruction 6 for procedure.

Potential persons who are to respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB number.