Ownership Submission
FORM 3
 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number: 3235-0104
Expires: January 31, 2005
Estimated average burden hours per response... 0.5

(Print or Type Responses)
1. Name and Address of Reporting Person *
  Greenman William Mariner
 2. Date of Event Requiring Statement (Month/Day/Year)
09/28/2006		 3. Issuer Name and Ticker or Trading Symbol
CERUS CORP [CERS]
(Last)
(First)
(Middle)
C/O CERUS CORPORATION, 2411 STANWELL DRIVE		 4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director _____ 10% Owner
__X__ Officer (give title below) _____ Other (specify below)
President, Cerus Europe
 5. If Amendment, Date Original Filed(Month/Day/Year)
(Street)

CONCORD, CA 94520		 6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4)		 2. Amount of Securities Beneficially Owned
(Instr. 4)		 3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)		 4. Nature of Indirect Beneficial Ownership
(Instr. 5)
Common Stock 76,026
D
 

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. SEC 1473 (7-02)
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 4)		 2. Date Exercisable and Expiration Date
(Month/Day/Year)		 3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)		 4. Conversion or Exercise Price of Derivative Security 5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)		 6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares
Option (Right to Buy)   (2) 03/18/2009 Common Stock 10,000 $ 22.75 D  
Option (Right to Buy)   (2) 05/10/2009 Common Stock 12,446 $ 16.25 D  
Option (Right to Buy)   (2) 05/10/2009 Common Stock 17,554 $ 16.25 D  
Option (Right to Buy)   (2) 01/02/2010 Common Stock 3,343 $ 24.875 D  
Option (Right to Buy)   (2) 01/02/2010 Common Stock 21,657 $ 24.875 D  
Option (Right to Buy)   (2) 03/20/2011 Common Stock 3,529 $ 38.1875 D  
Option (Right to Buy)   (2) 03/20/2011 Common Stock 16,471 $ 38.1875 D  
Option (Right to Buy)   (2) 03/19/2012 Common Stock 2,751 $ 50.18 D  
Option (Right to Buy)   (2) 03/19/2012 Common Stock 24,749 $ 50.18 D  
Option (Right to Buy)   (1) 12/19/2012 Common Stock 5,751 $ 21.06 D  
Option (Right to Buy)   (1) 02/28/2013 Common Stock 5,750 $ 6.75 D  
Option (Right to Buy)   (1) 06/30/2013 Common Stock 5,749 $ 7.52 D  
Option (Right to Buy)   (1) 11/13/2013 Common Stock 17,250 $ 4.25 D  
Option (Right to Buy)   (2) 03/30/2014 Common Stock 50 $ 3.52 D  
Option (Right to Buy)   (1) 06/28/2014 Common Stock 100,000 $ 2.28 D  
Option (Right to Buy)   (1) 10/02/2015 Common Stock 65,000 $ 8.86 D  
Option (Right to Buy)   (2) 01/02/2016 Common Stock 75 $ 10.15 D  

Reporting Owners

Reporting Owner Name / Address Relationships
Director 10% Owner Officer Other
Greenman William Mariner
C/O CERUS CORPORATION
2411 STANWELL DRIVE
CONCORD, CA 94520		       President, Cerus Europe  

Signatures

/s/ William M. Greenman 10/04/2006
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 5(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) One eighth (1/8th) of the shares subject to the Option shall vest six (6) months after the transaction date, and one forty-eighth (1/48th) of the shares subject to the Option shall vest on the first day of each month thereafter.
(2) Fully vested.

Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, See Instruction 6 for procedure.

Potential persons who are to respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB number.