UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                              WASHINGTON, DC 20549

                                  ------------


                                    FORM 8-K

                                 CURRENT REPORT
                     Pursuant to Section 13 or 15(d) of the
                         Securities Exchange Act of 1934


       Date of report (Date of earliest event reported): October 21, 2004


                       COMPUTER PROGRAMS AND SYSTEMS, INC.
               (Exact Name of Registrant as Specified in Charter)


         Delaware                        000-49796                74-3032373
(State or Other Jurisdiction         (Commission File           (IRS Employer
     of Incorporation)                    Number)            Identification No.)

           6600 Wall Street,                                        36695
            Mobile, Alabama                                      (Zip Code)
  (Address of Principal Executive Offices)

                                 (251) 639-8100
              (Registrant's telephone number, including area code)

                                       N/A
          (Former Name or Former Address, if Changed Since Last Report)

Check  the  appropriate  box  below  if the  Form  8-K  filing  is  intended  to
simultaneously  satisfy the filing obligation of the registrant under any of the
following provisions:

     |_|  Written  communications  pursuant to Rule 425 under the Securities Act
          (17 CFR 230.425)

     |_|  Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17
          CFR 240.14a-12)

     |_|  Pre-commencement  communications  pursuant to Rule 14d-2(b)  under the
          Exchange Act (17 CFR 240.14d-2(b))

     |_|  Pre-commencement  communications  pursuant to Rule 13e-4(c)  under the
          Exchange Act (17 CFR 240.13e-4(c))

Item 2.02.         Results of Operations and Financial Condition.

     On October 21, 2004, Computer Programs and Systems,  Inc. ("CPSI") issued a
press release announcing financial  information for its fiscal third quarter and
nine months ended  September 30, 2004.  The press release is attached as Exhibit
99.1 to this Form 8-K and is furnished to, but not filed with, the Commission.

Item 9.01.          Financial Statements and Exhibits.

(c)  Exhibits.

     Exhibit Number                 Exhibit
     --------------                 -------
     99.1                           Press Release dated October 21, 2004

                                   SIGNATURES

     Pursuant to the  requirements  of the Securities  Exchange Act of 1934, the
Registrant  has duly  caused  this  report  to be  signed  on its  behalf by the
undersigned hereunto duly authorized.


                                                             
                                       COMPUTER PROGRAMS AND SYSTEMS, INC.

                                       By: /s/ David A. Dye
                                           --------------------
                                           David A. Dye
                                           President and Chief Executive Officer


Dated: October 21, 2004

                                INDEX TO EXHIBITS

                                                 
Exhibit Number                        Exhibit
--------------                        -------
99.1                                  Press Release dated October 21, 2004 *


*    This  exhibit  is  furnished  to, but not filed  with,  the  Commission  by
     inclusion herein.