Whether you're looking to jump start a new weight loss program or just to drop those last few pounds before the summer, the best thermogenic fat burners below are a great place to start.
BOSTON, VIRGINIA / ACCESSWIRE / December 16, 2024 / If you're looking to burn fat and lose weight faster, a thermogenic fat burner can help accelerate your weight loss journey. The best fat burner supplements can help support your body's metabolism, suppress your appetite, increase energy, and burn calories faster.
Unfortunately, most fat-burning dietary supplements have unhelpful ingredients or aren't properly dosed for maximum results. To help you find the best thermogenic fat burner supplements, we've reviewed the top weight loss pills on the market.
Each of the best fat burners below were evaluated on a variety of factors including ingredients, dosage, safety, user reviews, and price. Whether you're looking to jump start a new weight loss program or just to drop those last few pounds before the summer, the best thermogenic fat burners below are a great place to start.
Best Thermogenic Fat Burners 2025
PhenQ: Best thermogenic fat burner overall
Capsiplex Trim: Top fat burning pills for women
Instant Knockout Cut: Best fat burner for men
CalmLean: Best non-stimulant fat burner
PhenQ PM: Best nighttime fat burner
PhenGold: Best alternative to prescription weight loss pills
Trimtone: Best appetite suppressant for women
Reviews of the Top Fat Burning Supplements
#1. PhenQ: Best Thermogenic Fat Burner Overall
If you look at any list for the best thermogenic fat burner, you'll likely find PhenQ earning consistently top marks. We rated PhenQ as our number one pick overall because it targets every aspect of weight loss, from your mental energy to your hunger cues, through powerful yet natural ingredients.
The thermogenic fat burner has over 190,000 satisfied customers and offers clinical trial data on formula ingredients to support its claims. All customers can enjoy free shipping with a 60-day money-back guarantee.
PhenQ Benefits
Losing body weight can take a toll on your mind and physical health. To help maintain a stricter diet and exercise routine, PhenQ keeps you in high spirits by offering comprehensive benefits. With the natural fat burner supplement, you can enjoy the following results:
Faster fat burning through thermogenesis, a process that kick starts your metabolism, allowing you to burn more calories at accelerated rates
Reduced weight gain to prevent you from accumulating more stored fat
Appetite suppression to help you stick to a healthy diet so you can see even better results
Reduced food cravings that often arise when you cut calories
Boosted energy levels that may drop from your lower caloric intake, allowing you to still enjoy full workouts
Balanced moods to help you stay positive during your weight loss journey, even as your hormones fluctuate
Formula Overview
α-Lacys Reset is the star of the PhenQ formula, a proprietary blend of alpha-lipoic acid, magnesium, a cysteine base, and other natural ingredients. The trademarked formula triggers thermogenesis while boosting your metabolism, allowing you to shed fat faster. In clinical trials, the primary ingredient in α-Lacys Reset allowed participants to enjoy a 3.44% reduction in body weight, a 7.24% drop in stored fat, and a 3.8% increase in muscle mass through improved energy effects.
PhenQ also contains critical natural ingredients like those found in Capsimax powder to induce thermogenesis, chromium picolinate (a cactus fiber) to curb appetites, and caffeine to help reduce cravings and increase energy after exercise.
How To Take PhenQ
The thermogenic fat burner manufacturer recommends taking PhenQ twice a day: once with breakfast and once with lunch. Because the fat-burning pills contain caffeine, you should avoid taking them before bed.
Who Is PhenQ For?
PhenQ is best for adults seeking a comprehensive, multi-targeting, effective fat burner. If you want to sharpen your mood and energy all day while losing weight, PhenQ may be for you.
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#2. Capsiplex TRIM: Best Fat Burner for Women
Capsiplex TRIM is a multi-targeting thermogenic fat burner designed to amplify your weight loss results so you can shed fat fast while maintaining muscle mass progress. The energizing fat-burning formula can help you finally melt stubborn belly fat while feeling energized enough to continue your gym progress.
The weight loss pill manufacturer offers a 60-day money-back guarantee, free shipping on all orders, and discount pricing on bulk purchases. You can read through reviews from the tens of thousands of satisfied customers who've tried and loved the fat-burning supplement.
Capsiplex TRIM Benefits
Capsiplex TRIM claims to help you achieve your weight loss goals by offering the following benefits:
Attacks fat to help you finally reduce the stubborn fat areas across your body
Fights fatigue with essential "energy nutrients" that help you recover from even the toughest workouts
Crushes cravings so you can stay on track with your healthy diet
Revs metabolism to increase your daily calorie burn so you can see results in just 12 weeks, according to manufacturer claims
Preserves muscles with vital rebuilding nutrients that keep your muscles healthy while your body focuses on burning fat
Ignites workouts so you can make more progress in the gym, even while consuming fewer calories
Formula Overview
Capsiplex TRIM uses one of the best thermogenic fat burner ingredients at a potent dose in its formula to kick your metabolism into high gear. Cayenne pepper (capsaicin) is a capsinoid that activates brown fat thermogenesis, allowing your body to burn more brown adipose tissue by increasing energy expenditure. According to clinical trials, the fat-burning ingredient can boost metabolism burn rates by up to 6%.
Capsiplex TRIM features numerous stimulating ingredients, like green tea extract and green coffee bean extract, to increase your metabolism by as much as 8%. The nutrient-dense formula also includes vitamins and minerals such as vitamins B6, B9, C, and D to keep your muscles healthy while losing weight and calcium, iron, and zinc for ideal performance.
How To Take Capsiplex TRIM
The manufacturer recommends taking the thermogenic fat burner on an empty stomach 30 minutes before going to the gym or half an hour before breakfast on your rest days. Follow this routine for 90 days until you see the full results.
Who Is Capsiplex TRIM For?
Capsiplex TRIM is the best weight loss pill for women hoping to fully realize all the hard work they put in at the gym. Losing weight can be a constant uphill battle, but Capsiplex TRIM helps you shed stubborn fat without compromising your hard-earned muscles.
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#3. Instant Knockout Cut: Best Thermogenic Supplement for Men
Instant Knockout Cut is one of the best thermogenic fat burner supplements for MMA fighters, athletes, boxers, bodybuilders, and anyone trying to achieve a sculpted, lean, and chiseled physique. The weight loss supplement features nine critical fat-burning ingredients to help you cut pounds fast while protecting your muscle gains.
Manufactured in an FDA-approved facility with all-natural, legal ingredients, Instant Knockout Cut offers scientifically researched potency and effectiveness. You can enjoy massive savings and free shipping if you order in bulk.
Instant Knockout Cut Benefits
Instant Knockout Cut claims you can enjoy the following benefits with its thermogenic fat burners:
Boosts metabolism, allowing you to burn more calories all day, even when you're resting after a tough workout
Reduces hunger so you can easily shed pounds before your next weigh-in without succumbing to cravings
Improves energy levels so you can enjoy the most intense, productive workouts of your life, even while consuming fewer calories
Formula Overview
The natural thermogenic fat burner uses a two-in-one formula to speed up your metabolism while curbing your appetite. One primary powerhouse appetite suppressant in the formula is glucomannan, a dietary fiber that helps your stomach stay full longer. The thermogenic fat burner also features ingredients like green tea extract and black pepper extract, essential components in speeding up thermogenesis so you can burn fat as much as 15% faster.
After taking Instant Knockout Cut, you won't have to worry about the classic caffeine slump because the formula also includes necessary amino acids, like L-theanine, to soothe jitters, prevent crashes, and promote sleep, so your body can get the rest it needs for ultimate muscle recovery.
As you lose weight, your body needs vitamins and minerals to nourish the muscles so you can reap all the benefits of your workout. Instant Knockout Cut includes natural ingredients like vitamins D3, B6, and D12 to keep you feeling your best before weighing in.
How To Take Instant Knockout Cut
The manufacturer recommends taking four capsules daily:
Right when you wake up
Between breakfast and lunch
One hour after lunch
One hour before dinner, but at least five hours before bed
Who Is Instant Knockout Cut For?
Instant Knockout Cut is for ambitious athletes struggling to see progress after all the hard work they put in at the gym. Losing weight while exercising can take a toll on your body and mind. Instant Knockout Cut gives you the energy and added boost to melt fat and nourish your muscles so you can achieve your body recomposition goals.
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#4. CalmLean: Best Non-stimulant Fat Burner
So far, every thermogenic fat burner on our list includes caffeine in its formula, which may be a helpful metabolism-boosting ingredient but can cause unwanted side effects, especially for sensitive individuals. If you struggle with caffeine jitters or prefer a weight loss supplement you can take at night, you need a stimulant-free fat burner. CalmLean is one of the best stimulant-free fat burners, offering effective weight loss results without any caffeinated ingredients.
CalmLean's manufacturer claims the weight loss supplement allows you to lose an additional one pound per week without changing your lifestyle. You can enjoy the 100% money-back guarantee if it doesn't work for you.
CalmLean Benefits
CalmLean features four non-stimulating all-natural thermogenic ingredients for suppressing appetite cues and igniting your internal furnace for ultimate fat loss. According to the manufacturer, you can enjoy the following benefits with CalmLean:
Boosts metabolism for faster weight loss results
Converts fat into energy so you can shed stubborn fat while feeling energized
Acts as an appetite suppressant so you can stick to your healthy diet goals
Blocks the formation of body fat cells so you can prevent further fat storage
Formula Overview
How does the thermogenic fat burner supplement achieve all of the above claims without stimulants? The all-natural stim-free formula contains four patented compounds to help you burn calories at an accelerated rate so you can lose fat without changing your lifestyle. The star ingredient, ForsLean, includes extracted Coleus forskohlii herb roots enhanced by a bioactive chemical process for more dramatic results.
In clinical trials, the primary ingredient in ForsLean helped patients lose weight without negative side effects. On average, participants lost an additional pound per week.
CalmLean also includes one of the best thermogenic fat burner ingredients, Capsicum annuum, which can boost your metabolism by as much as 20% in minutes. The final components in the formula include chromium picolinate for converting fat into muscle-building energy and the thermogenic "supercharger," BioPerine, to increase bioavailability.
How To Take CalmLean
When you're ready to burn excess fat with CalmLean, take two capsules daily with a glass of water. The fat-burning process requires no other changes to your daily life.
Who Is CalmLean For?
CalmLean is ideal for individuals seeking the best thermogenic fat burner supplement without stimulants. If you are prone to dizziness, heart palpitations, headache, nausea, jitters, or cramping when you ingest caffeine, CalmLean may be your answer.
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#5. PhenQ PM: Best Nighttime Fat Burner for Weight Loss
PhenQ PM is another one of the best non-stimulating thermogenic fat burners, offering all the power of an industry-leading weight loss supplement in a nighttime formula that allows you to burn fat while you sleep. The supplement goes beyond fat-burning benefits, helping you enjoy a more restful sleep so you can wake up energized for your day.
Like the original PhenQ, you can enjoy a 60-day money-back guarantee if you aren't fully satisfied with your purchase. All orders include free shipping and savings on bulk purchases. PhenQ PM is the highest rated nighttime fat burner .
PhenQ PM Benefits
Losing weight while you sleep may seem like a pipe dream, but PhenQ PM makes it a reality. The thermogenic weight loss pills claim to offer the following benefits:
Healthy weight loss support pushing you through all three stages of nighttime fat burning as your body enjoys a restful sleep
Improved levels of fat-burning hormones, raising your growth hormone while reducing cortisol levels with a solid night of sleep so your metabolism can operate at full speed
Reduced hunger so you can fight carb and sugar cravings to stick to your weight loss plans
Formula Overview
Sleep is an essential aspect of the weight loss process. A lack of sleep can harm your hormone levels, kill your energy, and more. PhenQ PM helps you burn fat by nourishing your body with sleep-inducing and hormone-balancing ingredients so you can naturally function at a peak metabolic rate.
To start, PhenQ PM features critical amino acids like L-arginine, L-lysine HCL, and L-theanine, which can all promote sleep, boost metabolism rates, reduce stress, suppress appetite levels, and convert fat into energy. To curb cravings and help you get a restful sleep without a grumbling stomach, the fat-burning formula includes 5-HTP, which can convert into serotonin in your body, acting as an appetite suppressant. You'll find numerous critical vitamins and nutrients on the ingredients label, like vitamins B1, B6, B5, and C, all nourishing your body through restful sleep as you burn fat.
How To Take PhenQ PM
The manufacturer recommends taking four capsules of PhenQ PM about 30 minutes to an hour before bed. Let the natural fat burners go to work as you sleep, then go about your daily routine with extra energy from your restful night.
Who Is PhenQ PM For?
PhenQ PM is best for busy parents, overworked individuals, anyone struggling to get restful sleep, or men and women who don't have time to focus on their diet but want to lose weight.
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#6. PhenGold: Highly Rated Diet Pills for Metabolism, Energy, and Fat-Burning
If you've ever considered a prescription weight loss drug but want to avoid the side effects, doctor visits, and other hassles, PhenGold may be for you. PhenGold is a clinically proven fat-burning supplement with maximum-strength ingredients designed to increase your metabolism and fat-burning hormones while suppressing appetite cues and hunger cravings so you can see substantial results.
All orders include a 100-day money-back guarantee with free shipping and discounts on bulk purchases. The U.S.-based manufacturer uses FDA-registered and GMP-certified facilities to produce the all-natural, non-GMO, vegan-friendly thermogenic fat burners.
PhenGold Benefits
PhenGold helps you enjoy the following fat-burning benefits:
Burns fat at more effective rates by switching on your fat-burning hormones
Boosts your metabolism to burn calories at faster rates so you can convert stored fat into useful energy
Curbs hunger and cravings so you can feel satisfied even while consuming less
Increases your focus and energy levels so you can tackle each day with the best foot forward, allowing you to avoid the common slumps that cause people to quit their diets
Enhances your daily moods so you can stay active, motivated, and positive
Formula Overview
Like all the best thermogenic fat burner supplements, PhenGold packs its formula with potent, natural ingredients. Caffeine, L-tyrosine, green tea extract, Rhodiola, and capsaicin increase your body's hormone-sensitive lipase, epinephrine, and adiponectin, allowing you to burn fat at faster rates. Caffeine offers numerous benefits in the formula, including its ability to boost metabolism by up to 11% and fat-burning rates by 29%.
The thermogenic fat burner ingredient, capsaicin, can also help you burn as much as 50 extra calories daily. Green tea extract boosts fat-burning rates by up to 17%.
The formula also includes critical nutrients, like vitamins B3, B6, and B12, to boost energy levels and moods, vital amino acids, appetite suppressants, and more. The well-rounded formula hits every base so you can lose weight while feeling mentally and physically great.
How To Take PhenGold
The thermogenic fat burner manufacturer recommends taking three capsules of PhenGold every morning at least 20 minutes before breakfast and ideally before your workout.
Who Is PhenGold For?
PhenGold is best for individuals seeking an alternative to prescription weight loss drugs, like phentermine. PhenGold allows you to reap the weight loss benefits without the side effects of harsh drugs.
Click Here for the Lowest Price on PhenGold
What Is a Thermogenic Fat Burner?
The best thermogenic fat burners are weight loss supplements that help your body generate more heat. When your body naturally burns calories, your metabolism generates heat using calories as fuel, ultimately converting your food into energy. When you don't have enough calories, your body will burn stored fat for energy, allowing you to lose weight.
Unfortunately, your metabolism slows with age, reduced exercise, hormone fluctuations, and other factors. The best thermogenic fat burners increase your body's internal furnace, allowing you to burn more calories at an increased rate so you can tap into your stored reserves without starving yourself. With the best fat burner supplements, you can burn more calories and fat while sedentary and after each workout.
Ample research supports how natural fat burners can aid in fat loss and prevent additional weight gain in obese individuals. So, how do thermogenic fat burners ignite your internal furnace? Fat burning supplements typically contain various clinically proven natural ingredients that promote thermogenesis.
Two categories of ingredients for thermogenic fat burners exist: those that directly boost your metabolism and those that increase your energy, motivating you to work out more so you can naturally boost your metabolism. Many of the thermogenic fat burners on our list include a mixture of both, targeting every aspect of your metabolism. The best thermogenic fat burners typically contain appetite suppressants, vitamins, and minerals to help you stick to your diet and feel healthy.
How Do Thermogenic Supplements Help With Weight Loss?
OTC weight loss pills often sound like the stuff of fantasy. So, how exactly do belly fat burners and thermogenic supplements help you lose weight? Fat burner pills target fat cells and weight loss in four critical ways:
Increased Thermogenesis
Thermogenic fat burner supplements help you lose weight by promoting thermogenesis, the process that ignites your metabolism.
Think about your body as a furnace. The furnace burns through calories for energy so your heart can beat and all your organs can function. When you reduce your calories, your body must tap into reserved fat to continue functioning properly.
When you have a fast metabolism, you can burn more calories, allowing you to lose fat at faster rates. By increasing thermogenesis, fat burner pills speed up your metabolism so you can melt body fat without significantly decreasing your caloric intake.
Appetite Suppression
Burning fat uses energy, which makes you hungrier. When you reduce your caloric intake, you may feel sluggish, starved, and tempted to succumb to sugar cravings, which can throw off your progress.
Belly fat burner supplements include natural appetite suppressant ingredients to help you feel satiated for longer periods so you aren't tempted to break your diet. Some ingredients in fat burning pills can boost serotonin responses so you no longer crave carbs and sugars as much, while other weight loss supplements include dietary fibers that expand in your stomach, helping you feel full for longer.
Increased Energy
When you lose weight, you may lose your energy, too. Exercise is a critical aspect of the weight loss process, though hitting the gym can feel impossible if you're fatigued. Thermogenic fat burners typically include energy-boosting ingredients that can push you through your workouts, naturally raising your metabolism rates.
Energy-boosting ingredients can include stimulants, like caffeine, or vitamins and minerals that nourish your body with the necessary components to feel your best. Occasionally, you may lack certain nutrients while on a diet, leading to fatigue. Fat burners replenish your body with these core nutrients so you can avoid the dreaded fatigue phase.
Fat Oxidation
Fat oxidation involves breaking down fat cells into smaller molecules that your body can use for energy. You can maximize the oxidation process through diet and exercise, though you must follow a strict regimen. Weight loss supplements aid in this process by helping your body break down fatty acids at an accelerated rate through thermogenesis.
Fatty acid oxidation is a critical step in the metabolic process, particularly in breaking down fatty tissue. All thermogenic fat burners boost fatty acid oxidation by increasing your body's internal furnace using the ingredients discussed below.
Common Ingredients Found in the Best Fat Burners
You may have noticed from our list of the best thermogenic fat burners that many formulas rely on similar ingredients. A few star components appear across labels as they are the most effective in targeting weight loss and burning stubborn belly fat. Review the most common ingredients in fat burners below to determine which options are right for you.
Caffeine
Caffeine is one of the most popular ingredients among the best fat burning supplements. Caffeine is a natural stimulant found in over 60 plants. Many consume caffeine by drinking coffee, green tea, soda, sports drinks, and more. Caffeine's primary effect is boosting your adrenaline levels, a hormone response that stimulates your fat cells to release fatty acids into your bloodstream to be converted into energy.
Caffeine can also reduce your appetite while boosting metabolism, making it a critical ingredient in many thermogenic fat burners for men. Clinical research shows that one milligram of caffeine can help you burn an extra 0.1 calories every 24 hours. Following this research, 150 milligrams can help you burn 15 calories per day without extra exercise.
Additional clinical studies further show that caffeine can increase your metabolism by as much as 11% while speeding up your fat-burning rates by 29%.
Green Tea Extract
Green tea extract is another common ingredient found in fat burning supplements. While green tea contains caffeine, it also includes the compound epigallocatechin gallate, which enhances the effects of caffeine by slowing down how your body breaks down adrenaline so you can enjoy more long-lasting results. Green tea can boost metabolism by up to 4% and fat-burning rates by 16%.
L-carnitine
L-carnitine is one of the best fat burning ingredients found in weight loss supplements. L-carnitine can help transport fatty acids into the mitochondria of your cells, allowing your cells to create more usable energy. In a review of 37 clinical research studies, L-carnitine helped participants lose significant weight, though it did not specifically target belly fat. On average, you can lose an extra 2.9 pounds with L-carnitine.
Glucomannan
Glucomannan is an appetite suppression ingredient found in many of the best thermogenic fat burners. Glucomannan is a dietary fiber that expands in your stomach, allowing you to feel full for longer periods. Research shows that you can lose an extra 5.5 pounds in a two-month span by taking glucomannan without changing any aspects of your diet or health.
Conjugated Linoleic Acid
While conjugated linoleic acid needs more research in human trials, it is a popular weight loss pill ingredient for many fat burner pills. Conjugated linoleic acid (CLA) is a naturally occurring fatty acid that may offer a fat-burning effect, though its results are inconsistent in humans. While the ingredient alone may not provide significant effects, it can offer an added boost when combined with the other powerful fat burners on this list.
Cayenne Pepper Extract
Cayenne pepper extract is a metabolism boosting ingredient found in many of the best fat burning pills. Cayenne pepper extract contains capsaicin, which produces spiciness in many foods. Capsaicin produces adrenaline responses similarly to caffeine, targeting your metabolism so you can burn more calories.
A clinical journal reviewing over 50 studies found that capsaicin can help you burn an extra 50 calories per day. Additional research shows the ingredient can support as much as 10% more fat loss after each meal.
Green Coffee Bean Extract
Green coffee bean extract is a stimulating ingredient from unroasted coffee beans, offering additional health benefits like antioxidants and weight loss effects. Clinical research shows that consuming green coffee bean extract can help you lose extra weight without changing other aspects of your health.
Frequently Asked Questions About Thermogenic Fat Burners
Do Thermogenic Fat Burners Work?
Yes, thermogenic fat burners can help you lose weight at an accelerated pace when combined with a healthy diet and exercise. The thermogenic ingredients help your body burn fat faster by boosting your metabolism, suppressing appetite cues, increasing your energy, and promoting fat oxidation.
Do Thermogenic Fat Burners Work Without Exercise?
Thermogenic fat burners typically do not work well without exercise. While a fat burner may promote a slight metabolic boost with some appetite suppression, you will not see substantial results without exercise. Exercising raises your metabolism naturally, amplifying the thermogenic effects.
Who Should Not Take a Fat-burning Supplement?
Anyone under 18, pregnant or breastfeeding, or taking prescription medications should not take a body fat burner supplement without consulting their doctor. Medications like blood thinners, antidepressants, and blood pressure medications can affect how fat burner supplements work. Anyone with diabetes, high blood pressure, heart disease, or thyroid problems should speak with a healthcare professional before taking a fat-burning supplement.
Are There Any Non-stimulant Fat Burners?
Yes, many non-stimulating fat burners offer excellent fat loss results without caffeine side effects. Popular non-stimulating fat burner options include CalmLean and PhenQ PM.
How Can I Get the Best Results With Thermogenic Fat Burners?
You can get the best results from your thermogenic fat burners by following the recommended dosage schedule and combining it with diet and exercise. Exercise can boost your metabolism, while a healthy diet helps you maintain a caloric deficit. Most fat burners work by amplifying your diet and exercise results.
Are Thermogenic Fat Burners Safe To Take?
Yes, natural thermogenic fat burners are safe because they include gentle ingredients that shouldn't cause adverse effects. If you are unsure, have a pre-existing condition, or take prescription medications, talk to your doctor first. Fat burners with stimulants may cause side effects in caffeine-sensitive individuals.
When Should I Consider Prescription Weight Loss Pills?
Doctors typically recommend considering prescription weight loss pills when your BMI is over 30. A few of the most popular options include bupropion-naltrexone, liraglutide, orlistat, and phentermine. PhenQ is the natural alternative to phentermine.
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