UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                    FORM 8-K

                                 CURRENT REPORT
                       Pursuant to Section 13 or 15(d) of
                       The Securities Exchange Act of 1934
       Date of report (Date of earliest event reported): November 2, 2004

                               VICAL INCORPORATED
               (Exact name of registrant as specified in charter)

          Delaware                     000-21088                  93-0948554
(State or other jurisdiction    (Commission File Number)      (I.R.S. Employer
      of incorporation)                                      Identification No.)

          10390 Pacific Center Court
             San Diego, California                                92121-4340
    (Address of principal executive offices)                      (Zip Code)

       Registrant's telephone number, including area code: (858) 646-1100

                                 Not Applicable.
         (Former name or former address, if changed since last report.)

Check the appropriate box below if the Form 8-K filing is intended to
simultaneously satisfy the filing obligation of the registrant under any of the
following provisions (see General Instruction A.2. below):

|_|   Written communications pursuant to Rule 425 under the Securities Act (17
      CFR 230.425)

|_|   Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR
      240.14a-12)

|_|   Pre-commencement communications pursuant to Rule 14d-2(b) under the
      Exchange Act (17 CFR 240.14d-2(b))

|_|   Pre-commencement communications pursuant to Rule 13e-4(c) under the
      Exchange Act (17 CFR 240.13e-4(c)) Item 2.02 Results of Operations and
      Financial Condition.



Item 2.02 Results of Operations and Financial Condition.

      On November 2, 2004, Vical Incorporated issued a press release announcing,
among other things, its financial results for the quarter ended September 30,
2004. A copy of the press release is attached as Exhibit 99.1 to this Current
Report.

      The information in this Item 2.02, and Exhibit 99.1 attached hereto, is
being furnished and shall not be deemed "filed" for the purposes of Section 18
of the Securities Exchange Act of 1934, as amended, or otherwise subject to the
liabilities of that section, nor shall it be deemed incorporated by reference in
any filing under the Securities Act of 1933, as amended, regardless of any
general incorporation language in such filing.



                                   SIGNATURES

      Pursuant to the requirements of the Securities Exchange Act of 1934, the
registrant has duly caused this report to be signed on its behalf by the
undersigned hereunto duly authorized.

                                           VICAL INCORPORATED

Date:  November 2, 2004                    By: /s/ JILL M. CHURCH             
                                               ---------------------------------
                                               Jill M. Church
                                               Vice President, Chief 
                                               Financial Officer and Secretary



                                INDEX TO EXHIBITS

Exhibit No.      Description

99.1             Press Release issued by Vical Incorporated on November 2, 2004.