SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549



                                    FORM 8-K
                                 CURRENT REPORT



     Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934



          Date of Report (Date of earliest event reported) May 4, 2004
                                                          ------------


                         Progenics Pharmaceuticals, Inc.
                 -----------------------------------------------
             (Exact name of registrant as specified in its charter)



          Delaware                     000-23143                 13-3379479
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(State or other jurisdiction          (Commission              (IRS Employer
     of incorporation)                File Number)           Identification No.)



        777 Old Saw Mill River Road, Tarrytown, New York      10591
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          (Address of principal executive offices)          (Zip Code)


        Registrant's telephone number, including area code (914) 789-2800
                                                          ----------------


           ---------------------------------------------------------
         (Former name or former address, if changed since last report.)



Item 7.  Financial Statements and Exhibits

(c)  Exhibits

      Exhibit 99.1                  Description
                           Press Release dated May 4, 2004 (filed herewith).


Item 9. Regulation FD Disclosure.

         On May 4, 2004, Progenics Pharmaceuticals,  Inc. issued a press release
announcing  the  initiation of a phase 1 clinical  trial of its  investigational
drug PRO 140, a humanized monoclonal antibody viral-entry inhibitor, designed to
prevent HIV (human  immunodeficiency  virus,  the causative  agent of AIDS) from
gaining  access to healthy cells of the human immune system by blocking the CCR5
coreceptor,  one of the principal portals HIV uses to enter cells. A copy of the
press release is attached as Exhibit 99.1.

         The information furnished pursuant to Item 9 in this Form 8-K shall not
be deemed  to be  "filed"  for the  purposes  of  Section  18 of the  Securities
Exchange Act of 1934 or otherwise  subject to the  liabilities  of that Section,
unless we specifically incorporate it by reference in a document filed under the
Securities Act of 1933 or the  Securities  Exchange Act of 1934. We undertake no
duty or  obligation  to  publicly  update or revise  the  information  furnished
pursuant to Item 9 in this Form 8-K.



                                   SIGNATURES

         Pursuant to the  requirements  of the Securities  Exchange Act of 1934,
the  registrant  has duly  caused  this report to be signed on its behalf by the
undersigned hereunto duly authorized.

                          PROGENICS PHARMACEUTICALS, INC.


                          By:  /s/ PHILIP K. YACHMETZ
                             -----------------------------------------
                                   Philip K. Yachmetz
                                   Vice President, General Counsel and Secretary


Date:  May 4, 2004