1. Title of Derivative Security (Instr. 4) |
2. Date Exercisable and Expiration Date (Month/Day/Year) |
3. Title and Amount of Securities Underlying Derivative Security (Instr. 4) |
4. Conversion or Exercise Price of Derivative Security |
5. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 5) |
6. Nature of Indirect Beneficial Ownership (Instr. 5) |
Date Exercisable |
Expiration Date |
Title |
Amount or Number of Shares |
Incentive Stock Option (right to buy)
|
Â
(2)
|
01/12/2016 |
Common Stock
|
2,900
|
$
5.46
|
D
|
Â
|
Incentive Stock Option (right to buy)
|
Â
(3)
|
01/26/2016 |
Common Stock
|
7,225
|
$
3.11
|
D
|
Â
|
Incentive Stock Option (right to buy)
|
Â
(4)
|
01/20/2017 |
Common Stock
|
14,329
|
$
9.41
|
D
|
Â
|
Incentive Stock Option (right to buy)
|
Â
(5)
|
05/17/2017 |
Common Stock
|
1,355
|
$
13.34
|
D
|
Â
|
Incentive Stock Option (right to buy)
|
Â
(6)
|
01/24/2018 |
Common Stock
|
8,030
|
$
14.72
|
D
|
Â
|
Incentive Stock Option (right to buy)
|
Â
(7)
|
01/18/2019 |
Common Stock
|
6,991
|
$
17.79
|
D
|
Â
|
Non-Qualified Stock Option (right to buy)
|
Â
(7)
|
01/18/2019 |
Common Stock
|
16,764
|
$
17.79
|
D
|
Â
|
Incentive Stock Option (right to buy)
|
Â
(8)
|
02/08/2020 |
Common Stock
|
7,458
|
$
18.32
|
D
|
Â
|
Non-Qualified Stock Option (right to buy)
|
Â
(8)
|
02/08/2020 |
Common Stock
|
39,208
|
$
18.32
|
D
|
Â
|
Incentive Stock Option (right to buy)
|
Â
(9)
|
01/20/2021 |
Common Stock
|
1,059
|
$
64.55
|
D
|
Â
|
Non-Qualified Stock Option (right to buy)
|
Â
(9)
|
01/20/2021 |
Common Stock
|
21,011
|
$
64.55
|
D
|
Â
|
* |
If the form is filed by more than one reporting person, see Instruction 5(b)(v). |
** |
Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a). |
(1) |
Includes 16,309 shares underlying restricted stock units ("RSUs") that will vest in full on April 8, 2017, subject to Dr. Huber's continued service with the Issuer through such vesting date. The RSUs may be settled only for shares of common stock on a one-for-one basis. |
(2) |
Beginning January 13, 2006, options become exercisable in 37 installments, with the first 25% vesting after one year and the remainder vesting monthly over three years. |
(3) |
Beginning January 27, 2009, options become exercisable in 25 installments, with the first 33.33% vesting after one year and the remainder vesting monthly over two years. |
(4) |
Beginning January 21, 2010, options become exercisable in 25 installments, with the first 33.33% vesting after one year and the remainder vesting monthly over two years. |
(5) |
Beginning May 18, 2010, options become exercisable in 25 installments, with the first 33.33% vesting January 21, 2011 and the remainder vesting monthly through January 21, 2013. |
(6) |
Beginning January 25, 2011, options become exercisable in 25 installments, with the first 33.33% vesting after one year and the remainder vesting monthly over two years. |
(7) |
Beginning January 19, 2012, options become exercisable in 25 installments, with the first 33.33% vesting after one year and the remainder vesting monthly over two years. |
(8) |
Beginning February 9, 2013, options become exercisable in 25 installments, with the first 33.33% vesting after one year and the remainder vesting monthly over two years. |
(9) |
Beginning January 21, 2014, options become exercisable in 25 installments, with the first 33.33% vesting after one year and the remainder vesting monthly over two years. |